Seachem StressGuard concentrated slime-coat protector 500 mL — pH-neutral wound and ammonia protection for freshwater & marine fis

Seachem StressGuard is a concentrated slime-coat protector that reduces handling stress and helps manage ammonia-related irritation in freshwater and marine fish.

Designed by hobbyists and scientists at Seachem, StressGuard is a ready-to-use colloidal formula created to protect exposed tissues, support wound recovery, and lower the effect of toxic ammonia when fish are transported, netted, or otherwise stressed. With over three decades of product development behind it, this 500 mL bottle offers an easy-to-dose solution you can add directly to quarantine, hospital, or display tanks without altering aquarium pH.

How does StressGuard protect fish during handling and transport?

StressGuard forms a protective colloidal coating that binds to exposed proteins on skin and gills, helping to shield tissues from irritants and reduce immediate stress responses. It works quickly and can be applied during netting, transfers, or while fish are in temporary holding containers.

• Applies directly to the water — no mixing required.
• Active colloidal agent targets exposed proteins on wounds and abrasions.
• Reduces irritation from ammonia and physical handling.
• Safe for use in freshwater and marine systems when dosed per instructions.

Will StressGuard interfere with aquarium chemistry or invertebrates?

StressGuard has a neutral pH of 7.0 and is formulated not to change aquarium pH even at higher doses, making it suitable for use in reef tanks and planted aquaria that include sensitive invertebrates. Always follow dosing guidance and monitor water parameters as part of routine care.

• pH neutral formula — will not alter tank pH.
• Safe for reef, planted, and community systems when used as directed.
• Dosing may be increased safely if needed; double doses are acceptable per product directions.
• Compatible with typical aquarium maintenance routines.

How should I dose StressGuard for best results?

Use 1/2 to 1 capful (2.5–5 mL) for every 40 L (10 US gallons) of water every 24 hours until stress signs or healing have improved. For acute handling events or heavy stress, the dose can be safely doubled for more immediate coverage. Apply directly to the tank or transport container water.

• Standard dose: 2.5–5 mL per 40 L (10 US gallons) every 24 hours.
• Safe to double the dose for increased protection during acute stress.
• Repeat daily until healing or stress indicators decline.
• For transport, add to holding water at the same dosing ratio.

How does StressGuard help wounds and reduce infection risk?

The colloidal component of StressGuard adheres to exposed proteins at wound sites, creating a protective matrix that encourages surface healing and improves contact between the wound and any disinfectant elements included in treatment plans. This targeted action helps reduce the chance of secondary infections while supporting recovery.

• Colloidal agent seeks out wounds and abrasions to coat exposed tissue.
• Helps deliver disinfectant contact where needed for improved efficacy.
• Supports formation of a temporary protective barrier over injuries.
• Useful as part of a broader treatment and quarantine routine.

Who this product is for: Seachem StressGuard is aimed at aquarium hobbyists, breeders, transporters, and retailers who need a reliable, science-backed product to reduce handling stress and protect fish during movement, quarantine, or recovery. It's helpful for anyone managing new arrivals, medicated treatments, or fish with minor injuries who wants a pH-stable, easy-to-dose option that integrates with routine aquarium care.