K9 Advantix II Extra Large Flea, Tick & Mosquito Treatment for Dogs Over 55 lbs — 6-Month, Monthly Spot-On, Water-Resistant

K9 Advantix II Extra Large Dog is a monthly, topical flea, tick, mosquito, biting fly and lice treatment and repellent formulated for dogs over 55 pounds.

If you want reliable, over-the-counter pest protection for a larger dog, K9 Advantix II delivers a once-a-month spot-on application designed to both kill and repel multiple external parasites. The formula works on contact to reduce the chance that fleas must bite to die, begins eliminating fleas quickly after the first dose, and becomes water-resistant after a full day. It's available in multi-dose packs so you can keep a steady regimen without a prescription.

How fast does K9 Advantix II start working on fleas?

The active ingredients begin affecting fleas shortly after application, with significant flea kill observed within the first 12 hours. Regular monthly applications stop new infestations by disrupting flea reproduction and lifecycle.

• Kills many adult fleas within 12 hours of initial use
• Applied topically to coat and skin for rapid contact action
• Monthly schedule helps prevent re-establishment of infestations

Will this product protect my large dog from ticks, mosquitoes and other biting pests?

K9 Advantix II is formulated to both kill and repel ticks, mosquitoes, biting flies and lice in addition to fleas. The dual kill-and-repel effect reduces the likelihood pests attach or feed, offering broad outdoor and indoor pest control when used as directed.

• Repels and kills multiple pests on contact
• Useful for dogs who spend time outdoors or in multi-pet homes
• Waterproof after 24 hours so normal activities won’t immediately remove protection

How is the treatment applied and what should I expect after application?

Application is a quick spot-on procedure applied to the skin between the shoulder blades so your dog can’t lick it off. The liquid spreads across the coat and skin and is non-fragrant; once absorbed it becomes water-resistant, and routine petting and play can resume soon after the solution dries.

• Spot-on pipette for easy, seconds-long application
• Fragrance-free formula that dries on contact with skin and coat
• Water-resistant after 24 hours — safe for normal activity afterward

Is this safe for my dog and how often should I use it?

K9 Advantix II is intended for dogs 7 weeks and older that weigh more than 55 pounds. Follow label directions for dosing and monthly reapplication; consult your veterinarian if your dog has known sensitivities, is pregnant, nursing, or has other health concerns.

• Designed for dogs over 55 lbs and at least 7 weeks old
• Apply once every 30 days for continuous protection
• Over-the-counter product — check the label for side effect and safety details

Who this is for: K9 Advantix II Extra Large Dog is aimed at owners of bigger dogs who want a convenient, monthly topical that controls fleas quickly and covers a range of biting pests without a prescription. It’s well suited for dogs that spend time both indoors and outdoors, multi-pet households, and owners who prefer a non-oral, easy-to-apply solution with waterproofing after 24 hours.

Ingredients

Imidacloprid 8.80% Permethrin* 44.00% Pyriproxyfen 0.44% Other Ingredients 46.76%