Frontline Plus Flea & Tick Spot Treatment for Large Breed Dogs 45–88 lbs (Purple) — 3-Pack, Waterproof 30-Day Protection

FRONTLINE Plus for Dogs (Large Breed, 45–88 lbs) is a monthly topical that helps kill fleas, flea eggs, flea larvae, ticks and chewing lice while providing waterproof protection for up to 30 days per dose.

This three-pack of FRONTLINE Plus (purple) is formulated for large-breed dogs weighing 45 to 88 pounds and delivers a single-point topical application that spreads through the skin’s oils to protect your pet over the course of a month. The formula combines active ingredients that target adult fleas and their immature stages, plus common tick species. It’s easy to apply at home and is designed to remain effective even if your dog gets wet after the treatment has been absorbed.

How quickly does this treatment start working?

Most pet owners see rapid results against adult fleas; the active ingredients begin affecting fleas soon after application. The product is also designed to interrupt the flea life cycle by targeting eggs and larvae, reducing the risk of reinfestation when used as directed.

• Designed for use once every 30 days per dose
• Targets adult fleas quickly and continues to act on eggs and larvae
• Deposits in sebaceous glands for ongoing release across the coat

Is FRONTLINE Plus waterproof, and can my dog swim after application?

After the formula has been absorbed and distributed through your dog’s skin oils, it remains effective even if your dog gets wet. Follow label directions for timing between application and bathing or swimming to ensure full absorption and optimal performance.

• Waterproof once absorbed into the skin’s natural oils
• Avoid bathing or heavy water exposure immediately after application per label guidance
• Continues to protect for a full 30 days under normal conditions

How do I apply the spot treatment correctly?

Apply the contents of one tube directly to your dog’s skin at a single spot—between the shoulder blades or another area the dog can’t easily lick. Part the hair to expose the skin and squeeze the applicator so the liquid contacts the skin; no need to rub it in. Using the correct dose and schedule helps maintain continuous protection for your household pets.

• Use one applicator per dog, once every 30 days
• Apply to skin, not just coat; part hair for direct contact
• Keep treated dogs away from children until dry

What pests does this formula address and how does it help households?

FRONTLINE Plus is formulated to kill adult fleas, flea eggs, flea larvae, ticks and chewing lice, reducing current infestations and helping prevent new ones when all household pets are treated appropriately. By breaking the flea life cycle and controlling ticks, it supports a practical approach to pest management for multi-pet homes.

• Kills adult fleas and immature flea stages to disrupt population growth
• Effective against common tick species and chewing lice
• Recommended to treat all pets in the home on schedule for best results

Who is this for: This three-dose pack is made for owners of large dogs between 45 and 88 pounds who want a monthly, easy-to-apply topical to manage fleas and ticks. It’s suited for households that need dependable, long-standing protection with a product intended to work across the flea life cycle. Always read and follow the label instructions and consult your veterinarian with any questions about suitability for puppies, pets with health issues, or concurrent medications.

Ingredients

Fipronil (9.8%)|(S)-Methoprene (8.8%)