Frontline Flea & Tick Spot Treatment for Medium Dogs 23–44 lb, 3-Count — Waterproof Monthly Protection

FRONTLINE Plus for medium dogs (23–44 lbs) is a monthly waterproof topical that helps eliminate adult fleas, flea eggs, flea larvae, chewing lice and ticks for up to 30 days per dose.

This three-count pack of FRONTLINE Plus is designed for medium-breed dogs weighing 23 to 44 pounds and delivers an easy single-point monthly application. Formulated with fipronil and (S)-methoprene, the treatment spreads across the skin via the sebaceous glands to work continuously and remains effective after bathing once applied. Trusted by pet owners for decades, it’s intended to break the flea life cycle while providing fast-acting relief and month-long coverage.

How quickly will I see results after applying FRONTLINE Plus?

Many dog owners notice a reduction in adult fleas within 24 hours and continued decline as the product targets eggs and larvae. The formula starts working on contact with adult fleas and then prevents future generations from developing.

• Reduces adult flea counts rapidly, often within a day.
• Disrupts egg and larval development to prevent re-infestation.
• One application protects your dog for approximately 30 days.

Is FRONTLINE Plus safe if my dog gets wet or swims?

After the product is applied and allowed to settle into the skin’s oil layer, it is designed to remain active even if the dog gets wet. Bathing immediately before or after application is not recommended; follow package timing instructions for best results.

• Waterproof once absorbed into the sebaceous glands.
• Replenishes on the skin naturally through oil glands.
• Follow label guidance on bathing timing around application.

How do I apply the spot treatment correctly?

Apply the liquid to a single spot on the dog’s skin so it can distribute across the body via natural oils. Part the hair between the shoulder blades and place the tip directly on skin to deliver the full dose.

• Part fur at the base of the neck between shoulder blades for a single-point application.
• Ensure tip touches skin, not just fur, to deposit the dose properly.
• Use one pipette per dog once a month for ongoing protection.

Will FRONTLINE Plus protect my whole household’s pets?

To control fleas and ticks effectively, treat all dogs and cats in the household with appropriate FRONTLINE formulations for their species and weight ranges. Consistent monthly use across pets helps prevent new infestations and reduces environmental flea stages.

• Use species-appropriate FRONTLINE products for cats and dogs.
• Treat every pet in the home monthly for best control.
• Combining treatment with good cleaning practices improves outcomes.

Who is this for: FRONTLINE Plus for medium dogs suits owners of single or multiple medium-breed dogs (23–44 lbs) who want a convenient, monthly topical that targets adult fleas, eggs and larvae, plus ticks and chewing lice. It’s a practical choice for families who bathe or swim with their dogs occasionally and prefer a water-resistant option delivered in an easy-to-apply single-point dose. If you need species- and weight-specific coverage across a household with cats and dogs, pair this with the appropriate FRONTLINE products for each pet.

Ingredients

Fipronil (9.8%)|(S)-Methoprene (8.8%)