Depend Night Defense Adult Diapers for Women, Medium 60-Count — Overnight 12-Hour Protection & Odor Control

Depend Night Defense Adult Diapers for Women are disposable overnight absorbent underwear designed to provide up to 12 hours of protection with odor control and a cotton-like, quiet fabric.

Engineered to help manage bladder leaks while you sleep, these medium-size Depend Night Defense underwear combine a high-capacity absorbent core with odor-neutralizing technology and softer materials for improved comfort. Each pack contains 60 pieces (four packs of 15) sized for a 31–37" waist. The design focuses on long-lasting dryness, discretion, and a familiar underwear fit so you can rest more comfortably through the night.

How does the absorbency keep me dry overnight?

Depend Night Defense uses a DryShield core made of super-absorbent material that absorbs many times its weight and locks fluids into a gel-like form. That rapid capture reduces moisture against skin and helps provide extended protection through hours of sleep.

• DryShield core absorbs up to 30x its weight and converts liquid into gel.
• Moisture-wicking layer moves liquid away from skin for comfort.
• Designed for up to 12 hours of overnight protection.

Will these feel like regular underwear or bulky adult diapers?

Depend Night Defense is made with a cotton-like, ultra-soft fabric that’s quieter and more flexible than some traditional adult diapers. The cut and materials aim to mimic regular underwear so movement, sleep, and dressing feel more natural.

• Underwear-like shape for familiar fit and ease of wear.
• Softer, quieter materials reduce rustling sounds at night.
• Disposable design for convenient wear and removal.

How does the product control odor?

These Depend underwear include ODORBLOCK technology engineered to neutralize and lock in odors rather than simply covering them. That helps reduce noticeable odors during extended wear and increases discretion.

• ODORBLOCK technology helps neutralize and lock in odors.
• Material construction limits odor release from the absorbent core.
• Packaged discreetly for private storage and travel.

What size and packaging should I expect, and how do I choose the right fit?

This listing is for size Medium, designed for a 31–37" waist, and includes 60 total underwear pieces divided into four packs of 15. Depend Night Defense is available in multiple sizes so you can select a size that matches your waist measurement for better comfort and performance.

• Size Medium fits 31–37" waist measurements.
• 60-count pack (4 packs of 15) for multi-night supply or trial use.
• Other sizes available: S, L, XL, XXL for varied waist ranges.

Who is this for: Depend Night Defense for Women is made for adults seeking overnight bladder leak protection with extended absorbency, odor management, and a more underwear-like feel. It suits those who want a discreet, comfortable disposable option for nights away from home or routine sleep, as well as people preferring softer, quieter materials over traditional, bulkier designs.