Depend Night Defense Adult Diapers for Women, Large 72 Count — Overnight 12‑Hour Protection & Odor Control

Depend Night Defense Adult Diapers for Women (Large, 72 count) are disposable overnight undergarments engineered to absorb heavy leaks and help you sleep up to 12 hours with odor control and underwear-like comfort.

These Depend Night Defense underwear combine a highly absorbent core, odor-neutralizing technology, and soft, cotton-like materials so you can rest without frequent changes. Designed specifically for overnight bladder leaks, the product converts liquid to gel and locks away moisture and odors while remaining quieter and more comfortable than traditional options.

How does this product handle nighttime leaks?

The DryShield core soaks up large volumes quickly and turns liquid into a gel to reduce pooling and shifting while you sleep. The design supports up to 12 hours of continuous protection, reducing the need for middle-of-the-night changes.

• Absorbent core captures up to 30× its weight in liquid*
• Gel-lock technology minimizes leakage and keeps surfaces drier
• 18–24-hour fit stability designed for overnight wear

Will these feel comfortable and discreet under pajamas?

Depend Night Defense is built with softer, quieter materials that mimic cotton for a more natural feel and reduced rustling. The underwear-like shape and fabric help create a discreet silhouette under sleepwear.

• Cotton-like outer fabric for a softer touch against skin
• Quieter materials that minimize crinkling during movement
• Underwear-style fit that sits like regular briefs

How does odor control work with Depend Night Defense?

ODORBLOCK technology targets and neutralizes odors so scents are locked away rather than simply masked. This provides improved confidence overnight and helps garments and bedding stay fresher between changes.

• Odor-neutralizing agents integrated into the absorbent layers
• Locks in odors to reduce noticeable scent escape
• Helps protect bedding and sleep environments from lingering smells

What sizes and counts are available, and what does this package include?

This listing is for size Large, which fits a 38–44" waist, and contains 72 disposable nighttime underwear. Depend Night Defense also comes in multiple sizes to match various body shapes and needs.

• Included: 72 pieces of Depend Night Defense for women, Large
• Size range options: S, M, L, XL, XXL (waist measurements listed on packaging)
• Designed for maximum overnight absorbency and comfort

Who is this for: Depend Night Defense is intended for women seeking reliable overnight protection from bladder leaks without sacrificing comfort. It suits anyone who prefers underwear-style disposable protection with strong absorbency, odor neutralization, and softer fabric for restful sleep. If you need daytime options, consider Depend Fresh Protection underwear for lighter, daytime wear.