Depend Night Defense Adult Diapers for Men — Large 56ct, Up to 12-Hour Leak Protection & Odor Control

Depend Night Defense Adult Diapers for Men in Large offer up to 12 hours of overnight leak protection with odor-neutralizing technology and underwear-like comfort.

Depend Night Defense is crafted to help men sleep through the night with confidence. These disposable incontinence underwear combine a highly absorbent DryShield core, odor-control technology, and soft, cotton-like materials to manage heavier bladder leaks while remaining quiet and comfortable under clothing. The large size fits waists 35–43 inches and the package contains 56 underwear (four packs of 14) for extended use.

How do these underwear manage overnight leaks?

Depend Night Defense is designed specifically for extended wear, using a super-absorbent DryShield core that locks in liquid and converts it into gel. This design helps reduce the risk of saturation and keeps the surface feeling drier for longer periods.

• DryShield core absorbs up to 30x its weight*
• Gel-locking technology holds liquid away from skin
• Engineered for up to 12 hours of protection

Will these reduce odor during the night?

Yes — Depend uses ODORBLOCK technology to help neutralize and lock in odors so nighttime odors are minimized. This lets users feel more confident around others and reduces the need for frequent changes solely due to smell.

• Integrated ODORBLOCK neutralizes common urinary odors
• Material composition helps contain smells within the core
• Continuous protection supports overnight use without frequent interruptions

Are they comfortable to wear compared to traditional adult diapers?

Depend Night Defense underwear are made to feel like regular underwear, using cotton-like fabric that’s softer and quieter than many disposable options. The fit and materials aim to reduce bulk and noise, improving discretion and overall comfort during sleep or daily activities.

• Cotton-like exterior fabric for a natural feel
• Soft, quieter materials to reduce rustling sounds
• An underwear-like cut designed for a discreet fit under clothing

How do I choose the right size and how many come in a pack?

The large size fits a 35–43 inch waist; Depend Night Defense is also available in small/medium and extra-large to accommodate different body types. This listing includes 56 pieces, split into four packs of 14 for easier storage and travel.

• Large size fits 35–43 inch waist
• 56 total underwear (4 packs of 14) for convenience
• Other sizes available: small/medium and extra-large

Who is this for: Depend Night Defense for Men, Large, is geared toward men who experience moderate to heavier nighttime bladder leaks and want a discreet, comfortable product that can be worn through sleep. It suits caregivers purchasing in bulk, individuals seeking odor control and long-lasting absorption, and anyone who prefers the feel of underwear-style protection rather than bulkier brief designs.

Packaging may vary. *Super absorbent material absorbs 30x its weight.