Advantage II Large Cat Flea Treatment for Cats Over 9 lbs — 6-Month Supply, Monthly Spot-On Protection

Advantage II Large Cat is a monthly topical flea treatment that kills adult fleas, larvae and eggs to protect cats over 9 lbs for 30 days per application.

Designed for cats at least 8 weeks old and weighing more than 9 pounds, Advantage II Large Cat is a vet-recommended, fragrance-free spot-on treatment that starts killing fleas within 12 hours and continues protecting your pet for a month. The easy squeeze-on applicator delivers the full dose directly to the skin at the base of the skull, is waterproof after 24 hours, and helps interrupt the flea life cycle by targeting all stages — adult fleas, larvae and eggs — to control infestations and reduce re-infestation risk.

How quickly does Advantage II start working and how long does it protect?

Once applied to the skin, Advantage II begins killing fleas through contact, usually within 12 hours. Each application remains effective for approximately 30 days, so monthly reapplication is needed to maintain continuous protection and break the flea life cycle.

• Onset: fleas begin dying within 12 hours
• Duration: protection lasts about 30 days per dose
• Maintenance: reapply every month for uninterrupted coverage

What stages of fleas does this treatment target and why does that matter?

Advantage II treats adult fleas, larvae and eggs, disrupting the flea life cycle so infestations decline over time. By killing immature stages as well as adults, it reduces the chance that surviving eggs or larvae will mature and repopulate your cat and environment.

• Adult fleas: knocked down quickly to stop biting and reproduce
• Larvae and eggs: eliminated to prevent new generations
• Environmental benefit: helps lower flea pressure in home and yard

How is Advantage II applied and is it safe and convenient for home use?

Application is a fast, one-step topical squeeze onto the skin at the base of the skull. There’s no need for pills or collars, and the formula is fragrance-free and becomes waterproof 24 hours after application. Always follow the label for correct dosage, handling and potential side effects.

• Application: place tube tip on skin and squeeze out full contents
• Convenience: quick spot-on method, no prescription required
• Water resistance: effective after 24 hours of drying

Can I use Advantage II on indoor and outdoor cats, and who should or shouldn't use it?

Advantage II is suitable for both indoor and outdoor cats that meet the age and weight requirements. It is intended for cats at least 8 weeks old and over 9 pounds; check the product label or consult your veterinarian for kittens, underweight animals, or if your cat has health concerns.

• Suitable for: cats 8+ weeks old and over 9 lbs, indoor or outdoor
• Not for: cats under the minimum age or weight without vet guidance
• Advice: consult your veterinarian for special health situations

Who is this for: Advantage II Large Cat is made for pet owners who want a fast, once-a-month flea solution for larger cats that interrupts the flea life cycle at multiple stages. It fits households seeking a vet-recommended, easy-to-apply topical treatment without pills or collars, and for anyone who prefers a fragrance-free, waterproof formula that can be purchased over the counter or via subscription for routine deliveries.

Ingredients

Imidacloprid: 9.10%, Pyriproxyfen: 0.46%, others ingredients 90.44%